PD Dr. med. Philipp Stein

2007: Dissertation an der Albert-Ludiwigs-Universität Freiburg im Breisgau (D)

2007: Medizinisches Staatsexamen an der Albert-Ludwigs-Universität Freiburg im Breisgau (D)

2007: Approbation als Arzt

2008: Assistenzarzt Anästhesiologie und Intensivmedizin, Universitätsspital Zürich

2009-2010: Assistenzarzt Institut für Anästhesiologie, Kantonsspital Winterthur

2010: Amerikanisches Medizinisches Staatsexamen (ECFMG)

2010-2012: Assistenzarzt Institut für Anästhesiologie, Universitätsspital Zürich

2012-2013: Assistenzarzt Innere Medizin, Kantonsspital Glarus

2013: Assistenzarzt Herzanästhesie Institut für Anästhesiologie, Universitätsspital Zürich

2013: Fähigkeitsausweis Notarzt SGNOR (re-zertifiziert)

2013/2014: Facharzt FMH Anästhesiologie (re-zertifiziert)

2014: Europäischer Facharzt EDAIC-DESA

2014-2019: Oberarzt Institut für Anästhesiologie, Universitätsspital Zürich

2018: Habilitation «Venia legendi» im Fach Anästhesiologie an der Universität Zürich

2019: Leitender Arzt Stv. Institut für Anästhesiologie, Kantonsspital Winterthur

2020-2022: Leitender Arzt Institut für Anästhesiologie, Kantonsspital Winterthur

2021-2022: Ärztlicher Leiter Rettungsdienst Institut für Anästhesiologie, Kantonsspital Winterthur

2014-2023: Ärztlicher Koordinator Rega Basis Mollis

2022-2023: Anästhesist Hirslanden Opera, incl. Kinderanästhesie

Seit November 2023: Stv. Chefarzt Anästhesie, Spital Linth

• 2008: PALS Provider (erster Kurs)
• 2008: ACLS Provider (erster Kurs)
• 2009: ATLS Provider (erster Kurs)
• 2010: Tierversuchsleiter (LTK 1/2 der Universität Zürich)
• 2010: «Good Clinical Practice» Module 1-3
• 2011: Perioperative transösophageale Echokardiographie
• 2011/2012: Gebirgsmedizinkurse
• 2013: ACLS Instruktor
• 2013: Leitender Notarzt SFG / CSAM
• 2013: Exminator Fachexamen der «European Society of Anaesthesiologists» (EDAIC)
• 2016: Weiterbildung Leadership (Unternehmerische Kompetenz, Führungs-/Sozialkompetenz), Universitätsspital Zürich
• 2018: Gastgeber Fachexamen Schweiz der EDAIC
• 2018: Lehrbeauftragter der Medizinischen Fakultät, Universität Zürich

• 2000: Jahrgangsbester im Fach Chemie
• 2018: Top 10 Artikel im Fachjournal «Anaesthesia» (Anästhesie Journal mit dem höchsten «Impact factor») 
• 2018: Abbvie Preis für die beste Publikation
• 2020: Abbvie Preis für die beste Publikation

• Swiss Society für Anaesthesiology and Perioperative Medicine (SSAPM)
• Schweizerische Gesellschaft für Notfall- und Rettungsmedizin (SGNOR)
• European Society of Anaesthesiologists (ESA)

• Humar M, Dohrmann H, Stein P, Andriopoulos N, Goebel U, Heimrich B, Roesslein M, Schmidt R, Schwer C I, Hoetzel A, Loop T, Pahl H L, Geiger K K, Pannen B H J (2007) Repression of T-cell function by thionamides is mediated by inhibition of the activator protein-1/nuclear factor of activated T-cells pathway and is associated with a common structure.
  Mol Pharmacol 72: 1647-1656
  Impact factor: 8.922 (2017)
• Humar M, Dohrmann H, Stein P, Andriopoulos N, Goebel U, Roesslein M, Schmidt R, Schwer C I, Loop T, Geiger K K, Pahl H L, Pannen B H J (2008) Thionamides inhibit the transcription factor nuclear factor-kappaB by suppression of Rac1 and inhibitor of kappaB Kinase alpha.
  J Pharmacol Exp Ther. 324: 1037-1044
  Impact factor: 3.867 (2017)
• Goebel U, Siepe M, Mechklenburg A, Stein P, Roesslein M, Schwer C I, Schmidt R, Doenst T, Geiger K K, Pahl H L, Schlensak C, Loop T (2008) Carbon monoxide inhalation reduces pulmonary inflammatory response during cardiopulmonary bypass in pigs.
  Anesthesiology. 108: 1025-1036
  Impact factor: 5.785 (2017)
• Siepe M, Goebel U, Mecklenburg A, Doenst T, Benk C, Stein P, Beyersdorf F, Loop T, Schlensak C (2008). Pulsatile Pulmonary Perfusion During Cardiopulmonary Bypass Reduces the Pulmonary Inflammatory Response.
  Ann Thorac Surg. 86: 115-122
  Impact factor: 3.700 (2017)
• Schwer C I, Stoll P, Pietsch U, Stein P, Laqua J, Goebel U, Hoetzel A, Schmidt R (2010) Up-regulation of heme oxygenase-1 by sevoflurane is not dependent on Kupffer cells and associates with ERK1/2 and AP-1 activation in the rat liver.
  Int J Biochem Cell Biol. 42: 1876-1883
  Impact factor: 3.505 (2017)
• Schmidt A R, Ulrich L, Seifert B, Albrecht R, Spahn D R, Stein P (2016) Ease and difficulty of pre-hospital airway management in 425 paediatric patients treated by a helicopter emergency medical service: a retrospective analysis.
  Scand J Trauma Resusc Emerg Med. 24: 22
  Impact factor: 2.036 (2017)
• Kaserer A*, Stein P*, Simmen H P, Spahn D R, Neuhaus V (2017) Failure rate of prehospital chest decompression after severe thoracic trauma.
  Am J Emerg Med. 35: 469-474
  Impact factor: 1.494 (2017)
• Oberholzer N, Kaserer A, Albrecht R, Seifert B, Tissi M, Spahn D R, Maurer K, Stein P (2017) Factors Influencing Quality of Pain Management in a Physician Staffed Helicopter Emergency Medical Service.
  Anesth Analg. 125: 200-209
  Impact factor: 4.014 (2017)
• Wetzel O, Schmidt A R, Seiler M, Scaramuzza D, Seifert B, Spahn D R, Stein P (2017) A smartphone application to determine body length for body weight estimation in children: a prospective clinical trial.
  J Clin Monit Comput. 68: 441-451
  Impact factor: 2.178 (2017)
• Stein P, Spahn G H*, Müller S, Zollinger A, Baulig W, Brüesch M, Seifert B, Spahn D R (2017) Impact of city police layperson education and equipment with automatic external defibrillators on patient outcome after out of hospital cardiac arrest.
  Resuscitation. 118: 27-34
  Impact factor: 5.230 (2017)
• Stein P, Kaserer A, Sprengel K, Wanner G A, Seifert B, Theusinger O M, Spahn D R (2017) Change of transfusion and treatment paradigm in major trauma patients.
  Anaesthesia. 72: 1317-1326
  Impact factor: 4.741 (2017)
• Steffensmeier D, Albrecht R, Wendling J, Melliger R, Spahn D R, Stein P, Wyss C (2017) Specialist advice may improve patient selection for decompression therapy following diving accidents: a retrospective observational study.
  Scand J Trauma Resusc Emerg Med. 25: 101
  Impact factor: 2.036 (2017)
• Stein P*, Studt J D*, Albrecht R, Müller S, von OW D, Fischer S, Seifert B, Mariotti S, Spahn D R, Theusinger O M (2018) The impact of prehospital tranexamic acid on blood coagulation in trauma patients.
  Anesth Analg. 126: 522-529
  Impact factor: 4.014 (2017)
• Grassin-Delyle S, Theusinger O M, Albrecht R, Müller S, Spahn D R, Urien S, Stein P (2017) Optimisation of the dosage of tranexamic acid in trauma patients with population pharmacokinetic analysis.
  Anaesthesia. 73: 719-729
  Impact factor: 4.741 (2017)
• Kaserer A, Casutt M, Sprengel K, Seifert B, Spahn D R, Stein P (2018) Comparison of two different coagulation algorithms on the use of allogeneic blood products and coagulation factors in  severely injured trauma patients.
  Scand J Trauma Resusc Emerg Med. 26: 4
  Impact factor: 2.036 (2018)
• Kaserer A, Schedler A, Jetter A, Seifert B, Spahn D R, Stein P, Studt J D (2018) Risk Factors for Higher-than-Expected Residual Rivaroxaban Plasma Concentrations in Real-Life Patients.
  Thromb Hemost. 118: 808-817
  Impact factor: 5.6
• Spahn DR, Schoenrath F, Spahn GH, Seifert B, Stein P, Theusinger OM, Kaserer A, Hegemann I, Hofmann A, Maisano F, Falk V (2019) Effect of ultra-short-term treatment of patients wirh iron deficiency or anaemia undergoing cardiac surgery: a prospective randomized trial.
  Lancet. 393: 2201-2212
• Kiavialaitis GE, Müller S, Braun J, Rössler J, Spahn DR, Stein P, Kaserer A (2019) Clinical practice of pre-hospital analgesia: An observational study of 20.978 missions in Switzerland.
  Am J Emerg Med. 18: S0735-6757
• Stein AL, Rössler J, Braun J, Sprengel K, Beeler PE, Spahn DR, Kaserer A, Stein P (2019) Impact of a goal-directed factor-based coagulation management on thromboembolic events following major trauma.
  Scand J Trauma Resusc Emerg Med. 30: 27
• Kaserer A, Schedler A, Seifert B, Spahn DR, Studt JD, Stein P (2019) Standard coagulation assays allone are not sufficient to exclude surgically relevant rivaroxaban plasma concentrations.
  Perioper Med (Lond). 8:15
• Ruch R, Stoessel L, Stein P, Ganter MT, Button DA (2019) Outcome, quality of life and direct costs after out-of-hospital cardiac arrest in an urban region of Switzerland.
  Scand J Trauma Resusc Emerg Med. 27: 106
• Füllenbach C, Stein P, Glaser P, Triphaus C, Lindau S, Choorapoikayil S, Schmitt E, Zacharowski K, Hintereder G, Hennig G, Hofmann C, Stepp H, Spahn GH, Kaserer A, Schedler A, Meybohm P, Spahn DR (2020) Screening for iron deficiency in surgical patients based on noninvasive zinc protoporphyrin measurements.
  Transfusion. 60: 62-72
• Kaserer A, Kiavialaitis GE, Braun J, Schedler A, Stein P, Rössler J, Spahn DR, Studt JD (2020) Impact of rivaroxaban plasma concentration on perioperative red blood cell loss.
  Transfusion. 60: 197-205
• Kelemen JA, Kaserer A, Jensen KO, Stein P, Seifert B, Simmen HP, Spahn DR, Neuhaus V (2020) Prevalence and outcome of contrast-induced nephropathy in major trauma patients.
  Eur J Trauma Emerg Surgery. ePub
• Tra S, Ochsenbein-Lälble N, Stein P, Meuli M, Moehrlen U, Mazzone L, Kraehenmann F, Zimmermann R, Biro P. Association of uterine activity and maternal volatile anesthetic exposure during open fetal surgery for spina bifida: a retrospective analysis. 
  Int J Obstet Anesth. 46: 102974
• Franke D, Zepf J, Burkhardt T, Stein P, Zimmermann R, Haslinger C. Retained placenta and postpartum hemorrhage: time is not everything.
  Arch. Gynecol Obstet. 304
• Stein P, Bosshart M, Brand B, Schlicker A, Spahn D R, Bettex D (2014) Dabigatran anticoagulation and Stanford type A aortic dissection: lethal coincidence: Case report with literature review.
  Acta Anaesthesiol Scand. 58: 630-637
  Impact factor: 2.438 (2017)
• Stein P, Albrecht R, Spahn D R (2014) Multiple trauma, resuscitation, and 15 minutes of esophagael intubation: survival without neurologic deficit.
  Am J Emerg Med. 32: 950.e1-2
  Impact facor: 1.494 (2017)
• Stein P, Meyer J, Mariotti S, Spahn D R, Albrecht R (2015) [Schwieriger präklinischer Atemweg und Bergung an der Rettungswinde.]
  Notarzt. 31: 129-133
  Impact factor: 0.318 (2017)
• Meyer S, Hartmann F, Stein P, Lenherr R, Fuchs J, Spahn D R (2017) Massive coagulopathy caused by the bite of a Crotalus basiliscus snake.
  Anaesth Cases. ePub
• Theusinger O M, Stein P, Spahn D R (2014) Applying «Patient Blood Management» in the trauma center.
  Curr Opin Anaesthesiol. 27: 225-232
  Impact factor: 2.369 (2017)
• Theusinger O M, Stein P, Spahn D R (2014) Transfusion strategy in multiple trauma patients.
  Curr Opin Crit Care. 20: 646-655
  Impact factor: 3.316 (2017)
• Spahn D R, Spahn G H, Stein P (2015) Evidence base for restrictive transfusion triggers in high-risk patients.
  Transfus Med Hemother. 42: 110-114
  Impact factor: 1.76 (2017)
• Theusinger O M, Stein P, Levy J H (2015) Point of Care and Factor Concentrate-Based Coagulation Algorithms.
  Transfus Med Hemother. 42: 1-7
  Impact factor: 1.76 (2017)
• Spahn D R, Spahn G H, Stein P (2015) Indications and Risks of Fibrinogen in Surgery and Trauma.
  Semin Thromb Hemost. 42: 147-154
  Impact factor: 3.629 (2017)
• Stein P, Kaserer A, Spahn G H, Spahn D R (2017) Point-of-Care Coagulation Monitoring in Trauma Patients.
  Semin Thromb Hemost. 43: 367-374
  Impact factor: 3.629 (2017)
• Spahn D R, Kaserer A, Spahn G H, Stein P (2017) «Patient Blood Management» ist heute Standard.
  Schweiz Med Forum. 17: 1145-1147
  Impact factor: 2.068 (2017)
• Kaserer A, Stein P, Spahn G H, Spahn D R (2017) Patient Blood Management: Der Standard heute
  Ther Umsch. 74: 369-376
  Impact factor: 0.18 (2017)

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